Presentation
PhD student
Victor is a PhD student in Mickaël Ménager’s laboratory. He has obtained his bachelor’s degree in biology in 2016 then his master’s degree in Immunology in 2018 at National Polytechnic Institute (Mexico). He worked, in Isabel Wong and Iris Estrada’s team in the laboratory of molecular Immunology II, on microvesicles released by M. tuberculosis and their capacity to trigger an immune response through human Toll-like receptors (2/6 and 4) expressed on HEK293 cells. By using the human granuloma in vitro model he highlighted the possible link between microvesicles and formation of sterile granulomas in chronic pulmonary tuberculosis.
In June 2018, he was auditioned for the international PhD program, supported by Bettencourt-Schueller and IMAGINE foundation and since November 2018 he’s part of Inflammatory responses and transcriptomic networks in diseases laboratory, managed by Mickaël Ménager.
Currently, he works on the role of CLOCK protein, known to establish circadian rhythm, in HIV-1 infection on a monocyte dendritic cells model in order to determine regulatory mechanisms for type I IFN production.
Resources & publications
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Journal (source)Cell Death Discov
Kremen1-induced cell death is regulated by homo- and heterodimerization.
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Journal (source)Curr. Opin. Neurobiol.
Cortical developmental death: selected to survive or fated to die.
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Journal (source)Evodevo
Neuronal fate specification by the Dbx1 transcription factor is linked to the...
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Journal (source)Curr. Biol.
Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Con...
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Journal (source)PLoS ONE
Dbx1-expressing cells are necessary for the survival of the mammalian anterio...
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Journal (source)PLoS Biol.
A novel role for Dbx1-derived Cajal-Retzius cells in early regionalization of...
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Journal (source)Cell Death Differ.
Kremen1 and Dickkopf1 control cell survival in a Wnt-independent manner.
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Journal (source)bioRxiv
Functional characterization of RELN missense mutations involved in recessive ...
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Journal (source)Development
The multiple facets of Cajal-Retzius neurons.
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Journal (source)Development
Single-cell transcriptomics of the early developing mouse cerebral cortex dis...
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Journal (source)Dev Cell
Repurposing of the multiciliation gene regulatory network in fate specificati...
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Journal (source)Curr Opin Neurobiol
Cajal-retzius cells: Recent advances in identity and function
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Journal (source)J Comp Neurol
Diversity within olfactory sensory derivatives revealed by the contribution o...
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Journal (source)Dev Cell
Repurposing of the multiciliation gene regulatory network in fate specificati...
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Journal (source)Dev Cell
Repurposing of the multiciliation gene regulatory network in fate specificati...
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Journal (source)J Clin Invest
De novo monoallelic Reelin missense variants act in a dominant-negative manne...
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Journal (source)J Clin Invest
De novo monoallelic Reelin missense variants cause dominant neuronal migratio...
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Journal (source)Development
Differential contribution of P73+ Cajal-Retzius cells and Reelin to cortical ...