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Research laboratories

Genetics of mitochondrial diseases

Genetic skin diseases : from disease mechanism to therapy

Genetics and development of the cerebral cortex

Chromatin and gene regulation during development

Clinical Bioinformatics Lab

Translational research for neurological disorders

Immunogenetics of pediatric autoimmune diseases

Molecular basis of altered immune homeostasis

Sigolène Meilhac

Human lymphohematopoiesis

Human genetics of infectious diseases : monogenic predisposition

Genetics in ophtalmology

Genome Dynamics in the Immune System

Embryology and genetics of malformations
Molecular and physiopathological bases of osteochondrodysplasia

Human genetics of infectious diseases : complex predisposition

Mechanisms and therapy of genetic brain diseases

Inflammatory responses and transcriptomic networks in diseases

Intestinal immunity

Molecular mechanisms of hematological disorders and therapeutic implications

Laboratory of Hereditary Kidney Diseases

Lymphocyte activation and susceptibility to EBV

Developmental Brain Disorders Laboratory

Neurogenetics and neuroinflammation

Research: a scientific adventure
Our goal: to better understand genetic diseases to better treat them.
Technological Platforms

Proteomic platform Necker

Genomics platform

Cell sorting facility

rAAV vectors platform

Necker DNA biobank

Cell Imaging Platform

LabTech Single-Cell@Imagine

IRM3T Plateform

iPSC core facility

Data science Plateform

Bioinformatic

Transgenesis Platform

The histology and morphology facility

Gene transfer vector core

1000 chercheurs au sein des équipes
209 brevets déposés
1 930 publications en France et à l'international
Associated Laboratories

Pr Nathalie Boddaert - Multimodal Brain Imaging Research and 3T Plateform

Molecular basis of several congenital or neonatal endocrine disorders and establishment of new therapeutic strategies

IMAG2 - Computational anatomy for image-guided minimally invasive surgery in pediatric tumoral and developmental diseases

Impact@Imagine – innovative multidisciplinary prenatal approach of congenital diseases and their treatments

La recherche clinique: un accelerateur d'innovations au benefice des patients
Clinical Research Service
Pr Jean-Marc Tréluyer

Clinical Research Plateform