Presentation
Tristan graduated from University Pierre & Marie Curie (Sorbonne University, France) where he obtained a Master degree in Biochemistry, in 2008. During his Master internship, he worked on microRNA interference in medulloblastoma in the team of Dr. Graeme Hodgson at University of California, San Francisco (USA).
He was recruited as junior technicia in the laboratory of Dr. Pierre-Louis Tharaux at PaRis Cardiovascular research Center (PaRCC, France), and then in the team of Dr. Marco Pontoglio at Cochin Institute (France) where he worked on kidney diseases.
In 2011, he worked in the laboratory of Dr. Pierre Charneau at Pasteur Institute (France), under the supervision of Dr. Anne-Sophie Beignon. He was in charge of a project focused on novel lentiviral vaccines to cure malaria, by which he acquired an expertise in immunology and virology. Then, he joined the laboratory of Pr. Claude Leclerc at Pasteur Institute, where he led a project focused on lentiviral vaccination.
In 2014, Tristan joined the laboratory of Dr. Annarita Miccio, where he is currently working on the development of innovative CRISPR/Cas9 based gene therapy strategies to treat β-hemoglobinopathies and on the epigenetic regulation during erythropoiesis.
Resources & publications
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Journal (source)Cell Death Discov
Kremen1-induced cell death is regulated by homo- and heterodimerization.
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Journal (source)Curr. Opin. Neurobiol.
Cortical developmental death: selected to survive or fated to die.
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Journal (source)Evodevo
Neuronal fate specification by the Dbx1 transcription factor is linked to the...
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Journal (source)Curr. Biol.
Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Con...
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Journal (source)PLoS ONE
Dbx1-expressing cells are necessary for the survival of the mammalian anterio...
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Journal (source)PLoS Biol.
A novel role for Dbx1-derived Cajal-Retzius cells in early regionalization of...
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Journal (source)Cell Death Differ.
Kremen1 and Dickkopf1 control cell survival in a Wnt-independent manner.
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Journal (source)bioRxiv
Functional characterization of RELN missense mutations involved in recessive ...
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Journal (source)Development
The multiple facets of Cajal-Retzius neurons.
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Journal (source)Development
Single-cell transcriptomics of the early developing mouse cerebral cortex dis...
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Journal (source)Dev Cell
Repurposing of the multiciliation gene regulatory network in fate specificati...
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Journal (source)Curr Opin Neurobiol
Cajal-retzius cells: Recent advances in identity and function
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Journal (source)J Comp Neurol
Diversity within olfactory sensory derivatives revealed by the contribution o...
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Journal (source)Dev Cell
Repurposing of the multiciliation gene regulatory network in fate specificati...
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Journal (source)Dev Cell
Repurposing of the multiciliation gene regulatory network in fate specificati...
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Journal (source)J Clin Invest
De novo monoallelic Reelin missense variants act in a dominant-negative manne...
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Journal (source)J Clin Invest
De novo monoallelic Reelin missense variants cause dominant neuronal migratio...
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Journal (source)Development
Differential contribution of P73+ Cajal-Retzius cells and Reelin to cortical ...