Publications and ressources

Phosphatase inhibition by LB-100 enhances BMN-111 stimulation of bone growth.

Nabil Kaci, Léa Loisay, Emilie Dambroise, Laurence Legeai-Mallet

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FGFR3 in Periosteal Cells Drives Cartilage-to-Bone Transformation in Bone Repair.

Caroline Carvalho, Laurence Legeai-Mallet

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Novel therapeutic approaches for the treatment of achondroplasia.

Laurence Legeai-Mallet

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Fgfr3 Is a Positive Regulator of Osteoblast Expansion and Differentiation During Zebrafish Skull Vault Development.

Emilie Dambroise, Ghaith ABDESSALEM, Marine LUKA, Laurence Legeai-Mallet , Mickaël Ménager

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Biallelic variants in KYNU cause a multisystemic syndrome with hand hyperphalangism.

Céline Huber, Valérie Cormier-Daire

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Homozygous Loss-of-Function Mutations in CCDC134 Are Responsible for a Severe Form of Osteogenesis Imperfecta.

Johanne Dubail, Geneviève Baujat, Céline Huber, Caroline Michot, Valérie Cormier-Daire

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Absence of GP130 cytokine receptor signaling causes extended Stüve-Wiedemann syndrome.

Céline Huber, Valérie Cormier-Daire

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Animal models of craniosynostosis.

Laurence Legeai-Mallet , Emilie Dambroise, Nabil Kaci

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Human IFT52 mutations uncover a novel role for the protein in microtubule dynamics and centrosome cohesion.

Sophie Saunier, Valérie Cormier-Daire, Cécile Jeanpierre, Meriem Garfa-Traoré , Patrick Nitschké

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Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.

Nabil Kaci, Meriem Garfa-Traoré , Emilie Dambroise, Laurence Legeai-Mallet

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Achondroplasia: Development, pathogenesis, and therapy.

Laurence Legeai-Mallet

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Early mandibular morphological differences in patients with FGFR2 and FGFR3-related syndromic craniosynostoses: A 3D comparative study

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